发明名称 |
METHODS FOR RESOLVING CONVOLUTED PEAKS IN A CHROMATOGRAM |
摘要 |
The present invention relates to methods for resolving convoluted peaks in a chromatogram into one or more constituent peaks using peak resolution values. The peaks methods of the invention determine empirical peak resolution values of “well-defined” or “isolated” peaks in the data, then extrapolate these empirical resolution values to peaks in neighboring regions to predict the number of constituent peaks at a given peak position. Predicted peak resolution values are compared to observed peak resolution values of low-resolution or convoluted peaks to determine the number of constituent peaks in the convoluted peaks. These methods enable extension of the region of data that can used for identifying nucleotide sequences, and increase base-calling accuracy in the low-resolution region (end region) of data. |
申请公布号 |
EP1997050(A4) |
申请公布日期 |
2015.07.22 |
申请号 |
EP20070763418 |
申请日期 |
2007.02.06 |
申请人 |
SIEMENS HEALTHCARE DIAGNOSTICS INC. |
发明人 |
IZMAILOV, ALEXANDRE, M.;YUWARAJ, MURUGATHAS |
分类号 |
G06F19/24;G01N30/86 |
主分类号 |
G06F19/24 |
代理机构 |
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地址 |
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