Heart valve prosthesis with collapsible valve and method of delivery thereof

摘要

A valve prosthesis is adapted to operate in conjunction with native heart valve leaflets. The prosthesis includes an annulus and a skirt extending from the annulus. The skirt may be configured to be positioned through a native heart valve annulus, and the skirt may be movable between an open configuration permitting blood flow through the skirt and a closed configuration blocking blood flow through the skirt in cooperation with opening and closing of the native heart valve leaflets.

主权项

1. A valve prosthesis comprising:
a frame element configured for positioning at or near a native heart valve annulus, over native heart valve leaflets, shaped to prevent the frame element from shifting downstream of the native heart annulus; a skirt attached to said frame element, the skirt being configured to be positioned through the native heart valve, the skirt being movable between an open configuration permitting blood flow through the skirt and a closed configuration blocking blood flow through the skirt in cooperation with opening and closing of the native heart valve leaflets; and at least two skirt support extensions attached to the frame, all the skirt support extensions configured and circumferentially arranged to extend through the skirt at ends of commissures of the native heart valve between the native heart valve leaflets, where the native heart valve leaflets meet, while preserving the function of the opening and closing of the native heart valve leaflets, and prevent the skirt from collapsing back from a downstream direction to an upstream direction.