LORCASERIN SALTS AND CRYSTALS THEREOF, PREPARATION METHODS AND USES THEREOF

摘要

Disclosed in the present application are the following crystals of Lorcaserin: sulfamate, stearate, cholate, 4-aminobenzene sulfonate, or terephthalate, and the preparation methods and pharmaceutical compositions thereof, and the uses thereof in the preparation of drugs for treating and/or preventing diseases associated with 5HT2c, such as obesity. The release rate index in water of sustained release tablets of the crystals has improved properties.