| 摘要 |
[Problem] To provide a useful dipeptide-containing composition derived from dried bonito flakes and the like, having an angiotensin-converting-enzyme inhibiting activity that imparts a blood pressure reducing function. [Solution] A composition containing a dipeptide derived from a fish meat protein having an angiotensin-converting-enzyme inhibiting activity. The composition is characterised by containing: at least one type of dipeptide selected from the group consisting of a dipeptide consisting of a tryptophan-leucine amino acid sequence, a dipeptide consisting of a leucine-tryptophan amino acid sequence, a dipeptide consisting of a tryptophan-isoleucine amino acid sequence, a dipeptide consisting of a valine-triptophan sequence, a dipeptide consisting of a tryptophan-tyrosine sequence, a dipeptide consisting of a tryptophan-methonine sequence, a dipeptide consisting of a serin-triptophan sequence, and a dipeptide consisting of an asparagine-triptophan sequence; and/or an acid addition salt of said dipeptide(s). |
| 主权项 |
1. A composition characterized by being derived from a fish meat protein of a bonito, a roughly dried bonito, a really dried bonito, a frigate mackerel, a dried frigate mackerel, a sardine, a dried sardine, a saurel, a dried saurel, a mackerel, a dried mackerel, a dried small sardine, or the other a miscellaneous dried fish, and comprising a dipeptide having an angiotensin converting enzyme inhibitory activity, wherein the dipeptide comprises at least one dipeptide selected from a group consisting of
a dipeptide composed of a tryptophan-leucine amino acid sequence, a dipeptide composed of a leucine-tryptophan amino acid sequence, a dipeptide composed of a tryptophan-isoleucine amino acid sequence, a dipeptide composed of a valine-tyrosine amino acid sequence, a dipeptide composed of a tryptophan-asparagine amino acid sequence, a dipeptide composed of a valine-tryptophan sequence, a dipeptide composed of a tryptophan-tyrosine sequence, a dipeptide composed of a tryptophan-methionine sequence, a dipeptide composed of a methionine-tryptophan sequence, a dipeptide composed of a isoleucine-tryptophan sequence, a dipeptide composed of a serine-tryptophan sequence, a dipeptide composed of an asparagine-tryptophan sequence, a dipeptide composed of a glutamine-tryptophan sequence, a dipeptide composed of a glycine-tryptophan sequence and a dipeptide composed of an alanine-tryptophan sequence, and/or acid addition salts thereof. |
