| 发明名称 |
NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME |
| 摘要 |
Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases. |
| 申请公布号 |
EP2888268(A1) |
申请公布日期 |
2015.07.01 |
| 申请号 |
EP20130846040 |
申请日期 |
2013.10.04 |
| 申请人 |
OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION |
发明人 |
CUI, HAI-LEI;TANAKA, FUJIE |
| 分类号 |
C07D491/107;A61K31/407;A61P35/00 |
主分类号 |
C07D491/107 |
| 代理机构 |
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