Systems and methods for valving on a sample processing device

摘要

A system and method for valving on a sample processing device. The system can include a valve chamber, a process chamber, and a valve septum located between the valve chamber and the process chamber. The system can further include a fluid pathway in fluid communication with an inlet of the valve chamber, wherein the fluid pathway is configured to inhibit a liquid from entering the valve chamber and collecting adjacent the valve septum when the valve septum is in a closed configuration. The method can include rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the valve chamber; forming an opening in the valve septum; and rotating the sample processing device to exert a second force on the liquid to move the liquid into the valve chamber.

主权项

1. A valving structure on a sample processing device, the valving structure comprising:
a valve chamber; a process chamber positioned to be in fluid communication with an outlet of the valve chamber; a valve septum located between the valve chamber and the process chamber and vertically above at least a portion of the valve chamber, with respect to a vertical thickness of the sample processing device, the valve septum having:
a first side oriented substantially horizontally with respect to the vertical thickness of the sample processing device,a second side, opposite the first side, oriented substantially horizontally with respect to the vertical thickness of the sample processing device,a closed configuration wherein the valve chamber and the process chamber are not in fluid communication, andan open configuration in which an opening or void is formed in the valve septum and the valve chamber and the process chamber are in fluid communication,wherein the valve septum is configured to be changed from the closed configuration to the open configuration by directing electromagnetic energy at the first side of the valve septum; and a fluid pathway in fluid communication with an inlet of the valve chamber, wherein the fluid pathway is configured to inhibit a liquid from entering the valve chamber and collecting adjacent the second side of the valve septum when the valve septum is in the closed configuration.