摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to 5,5-condensed heteroarylene compoundsIIIB, where U, V, Vand Ware selected from O, N, NH, S or CR; U, W, Xand Xrepresent C or N; Rand Rrepresents hydrogen, -C(O)CH(NRR)R, -C(O)CH(N(R)C(O)OR)Ror -C(O)OR; Rrepresents hydrogen or R; Rrepresents halogen or -C(O)OR; Land Lare such as given in invention formula, each Zand Zrepresents bond or -O-; each R, Rand Rrepresents hydrogen, Calkyl or Caryl; or Rand Rtogether with N atom, which they are bound to, form 5-6-membered heterocyclyl; q, r, s, t and u equal 1. Invention also relates to pharmaceutical compositions, containing 5,5-condensed heteroarylene compounds, and methods of treating or preventing HCV infection.EFFECT: 5,5-condensed heteroarylene derivatives, possessing inhibiting activity with respect to hepatitis C virus.43 cl, 42 ex |