| 摘要 |
Compounds containing at least one nitrile functional group are produced by hydrocyanation of an organic compound having at least one site of non-conjugated unsaturation, having from 2 to 20 carbon atoms, by reaction with hydrogen cyanide in the presence of a catalytic system containing a complex of nickel having the oxidation state of zero with at least one organophosphorus ligand selected from the group consisting of organophosphites, organophosphonites, organophosphinites and organosphosphines and a cocatalyst of the Lewis acid type of formula:;
in which M1 and M2 are each elements selected from the group consisting of zinc, boron, aluminum, cadmium, gallium, indium and tin. |
| 主权项 |
1. A process for the preparation of a compound containing at least one nitrile functional group, comprising the hydrocyanation of an organic compound having at least one site of non-conjugated unsaturation, having from 5 to 20 carbon atoms, by reaction with hydrogen cyanide in the presence of a catalytic system which comprises a complex of nickel having the oxidation state of zero with at least one organophosphorus ligand selected from the group consisting of organophosphites, organophosphonites, organophosphinites and organosphosphines and a cocatalyst, wherein the cocatalyst is an organometallic compound corresponding to general formula (I):in which:
R1 and R3, which are identical or different, are each a branched or unbranched, aliphatic organic radical, a substituted or unsubstituted, aromatic or cycloaliphatic radical, or a halogen atom, M1, M2, which are identical or different, are each an element of valency m1, m2, respectively, selected from the group consisting of zinc, boron, aluminum, cadmium, gallium, indium and tin, with the proviso that M1 and M2 cannot simultaneously each be boron, X is oxygen, n is an integer equal to m1−1, and p is an integer equal to m2−1. |
