| 发明名称 |
GENERATION OF HEPATOCYTES FROM PLURIPOTENT STEM CELLS |
| 摘要 |
Methods are provided for producing differentiated cells from stem cells, including producing hepatocytes. Compositions thereof are also provided, as are methods of treating a liver disorder. |
| 申请公布号 |
US2015166953(A1) |
申请公布日期 |
2015.06.18 |
| 申请号 |
US201314409234 |
申请日期 |
2013.06.27 |
| 申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
Gupta Sanjeev;Bandi Sriram |
| 分类号 |
C12N5/071;A61K35/407 |
主分类号 |
C12N5/071 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of producing a differentiated cell from a pluripotent stem cell, the method comprising maintaining the pluripotent stem cell in a medium comprising two or more of phenacetin, phytosphingosine HCl, and pyridoxal HCl, or a medium comprising conditioned medium from hepatoblasts, for a time sufficient to produce the differentiated cell. |
| 地址 |
Bronx NY US |
