发明名称 |
CLASSIFIERS OF NF-kB PATHWAY ACTIVATION, DEVICES, AND METHODS OF USE THEREOF |
摘要 |
This disclosure relates to classifiers of NF-κB pathway activation, devices, and methods of use thereof. In certain embodiments, the disclosure relates to methods comprising measuring changes in expression of genes controlled by p105 in a sample providing a detected p105 controlled gene expression pattern. In certain embodiments, the methods further comprise measuring changes in expression of genes controlled by p100 in a sample providing a detected p100 controlled gene expression pattern. In certain embodiments, the methods further comprise the step of comparing the detected p105 controlled gene expression patterns to a predetermined gene pattern and/or the detected p100 controlled gene expression patterns to a predetermined pattern. |
申请公布号 |
US2015167097(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
US201314414507 |
申请日期 |
2013.09.20 |
申请人 |
EMORY UNIVERSITY |
发明人 |
Bernal-Mizrachi Leon |
分类号 |
C12Q1/68;A61K45/06;A61K39/395 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
1. A method comprising measuring changes in expression of genes controlled by p105 in a sample providing a detected p105 controlled gene expression pattern. |
地址 |
Atlanta GA US |