发明名称 |
A METHOD FOR ASSAYING THE ACTIVITY OF SPERMIDINE/SPERMINE N1-ACETYLTRASFERASE |
摘要 |
A method for assaying activity of the enzyme spermidine/spermine N1-acetyltransferase (SSAT) uses SSAT substrates by detecting their acetylated forms. SSAT substrates may include rimantadine and tocainide wherein their metabolism occurs in part by the action of the inducible enzyme SSAT to produce the acetylated metabolites N-acetylrimantadine and N-acetyltocainide respectively. SSAT activity may be correlated to pathologic conditions. |
申请公布号 |
EP2788498(A4) |
申请公布日期 |
2015.06.17 |
申请号 |
EP20120850541 |
申请日期 |
2012.11.16 |
申请人 |
BIOMARK TECHNOLOGIES INC. |
发明人 |
CHENG, BRIAN;BUX, RASHID;SITAR, DANIEL |
分类号 |
C12Q1/48;G01N33/574 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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