发明名称 |
TRPV1 inhibitory peptides and composition for skin-aging protection or wrinkle improvement comprising the same |
摘要 |
TRPV1 inhibitory peptide and a composition thereof for skin-aging prevention, wrinkle improvement, skin-whitening, or alleviating inflammation, irritation or pain is described, where the TRPV1 inhibitory peptide inhibits the expressions of MMP and proinflammatory cytokines induced by UV exposure and reduces skinfold thickness and intracellular Ca2+influx. |
申请公布号 |
US9056889(B2) |
申请公布日期 |
2015.06.16 |
申请号 |
US201313855022 |
申请日期 |
2013.04.02 |
申请人 |
SNU R&DB FOUNDATION |
发明人 |
Chung Jin Ho;Kang So Min;Lee Young Mee;Lee Se Rah;Kim Yeon Kyung |
分类号 |
A61K8/64;A61K35/36;A61K38/08;A61Q19/02;A61Q19/08;C07K7/06;G01N33/50;G01N33/68 |
主分类号 |
A61K8/64 |
代理机构 |
Vorys, Sater, Seymour and Pease LLP |
代理人 |
Vorys, Sater, Seymour and Pease LLP ;Koh Mihsun |
主权项 |
1. An isolated peptide inhibiting transient receptor potential vanilloid type 1 (TRPV1) activity, consisting of the peptide as set forth by SEQ ID NO: 2 or SEQ ID NO: 4. |
地址 |
Seoul KR |