发明名称 SKIN EXTERNAL AGENT FORMULATION CONTAINING HIGH CONCENTRATED HYALURONIC ACID AND PREPARING METHOD THEREOF
摘要 The present invention relates to an external use skin composition containing high concentrated hyaluronic acid and a method of preparing the same and, more specifically, to an external use skin composition which contains high concentrated hyaluronic acid having high water retaining property, has small molecular weight and low viscosity to provide superior usability, and also prevents microbial contamination without an antiseptic. The external use skin composition prepared by a method according to the present invention contains high concentrated hyaluronic acid which has high water retaining property, small molecular weight and low viscosity, to be employed in various applications, such as a spray, to demonstrate superior moisturizing effect by being easily absorbed into the skin, and to prevent microbial contamination without an additional antiseptic. A method of preparing the external use skin composition may comprise the steps of: (a) applying heat or gamma ray to high-molecular hyaluronic acid whose molecular weight is 500-3000 kDa, to prepare low-molecular hyaluronic acid whose L value is 98 or more, b value is 3.5 or less and molecular weight is 100-300 kDa; (b) dissolving the low-molecular hyaluronic acid in purified water to manufacture 2-5 wt% of a hyaluronic acid solution; and (c) heating the hyaluronic acid solution under temperature 80-100°C to prepare a hyaluronic acid solution whose viscosity is 50-150 cps and molecular weight 10-30 kDa.
申请公布号 KR20150064454(A) 申请公布日期 2015.06.11
申请号 KR20130149205 申请日期 2013.12.03
申请人 JINWOO BIO CO., LTD. 发明人 KWEON, DONG KEON
分类号 A61K31/728;A61P17/00 主分类号 A61K31/728
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