发明名称 HDAC阻害剤
摘要 <p>This invention provides the compound having the structure wherein n is 1-10; X is C—R11 or N, wherein R11 is H, OH, SH, F, Cl, SO2R7, NO2, trifluoromethyl, methoxy, or CO—R7, wherein R7 is alkyl, alkenyl, alkynyl, C3-C8 cycloalkyl, or aryl; Z is R2 is H or NR3R4, wherein R3 and R4 are each independently H, C1-C6 alkyl, or C3-C8 cycloalkyl; R5 is OH or SH; and R6, R12, R13, and R14 are each independently H, OH, SH, F, Cl, SO2R15, NO2, trifluoromethyl, methoxy, or CO—R15 wherein R15 is alkyl, alkenyl, alkynyl, C3-C8 cycloalkyl, or aryl, or a salt of the compound, which is useful in the treatment of tumors.</p>
申请公布号 JP5730575(B2) 申请公布日期 2015.06.10
申请号 JP20100527975 申请日期 2008.10.01
申请人 发明人
分类号 C07C323/62;A61K31/167;A61K31/4406;A61K31/455;A61K31/609;A61P1/16;A61P3/10;A61P29/00;A61P33/02;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07C319/12;C07D213/75;C07D213/83 主分类号 C07C323/62
代理机构 代理人
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