发明名称 |
Absorbable crystalline copolyester-based bioactive hydroforming luminal liner compositions |
摘要 |
Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty. |
申请公布号 |
US9050366(B2) |
申请公布日期 |
2015.06.09 |
申请号 |
US201313754110 |
申请日期 |
2013.01.30 |
申请人 |
Poly-Med, Inc. |
发明人 |
Shalaby Shalaby W.;Hilas Georgios T.;Gray Kenneth David |
分类号 |
A61K47/34;A01N25/34;B65D65/38;A61K9/00;A61K31/12;A61K31/192;A61K31/337;A61K31/4025;A61K31/4164;A61K31/4174;A61K31/427;A61K31/436;A61K31/497;A61K31/506;A61K31/65;A61K31/7036;A61M25/04;A61M31/00;A61M25/00 |
主分类号 |
A61K47/34 |
代理机构 |
McNair Law Firm, P.A. |
代理人 |
McNair Law Firm, P.A. ;Lineberry Douglas L. |
主权项 |
1. A bioactive, hydroforming, luminal liner composition comprising at least one crystalline, absorbable copolyester having a heat of fusion of at least 10 J/g and a molecular weight of greater than of 20 kDa; at least one liquid derivative of a polyether glycol; and at least one bioactive agent comprising an antifungal agent selected from the group consisting of ketoconazole, miconazole, voriconazole, and fluconazole. |
地址 |
Anderson SC US |