发明名称 Absorbable crystalline copolyester-based bioactive hydroforming luminal liner compositions
摘要 Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
申请公布号 US9050366(B2) 申请公布日期 2015.06.09
申请号 US201313754110 申请日期 2013.01.30
申请人 Poly-Med, Inc. 发明人 Shalaby Shalaby W.;Hilas Georgios T.;Gray Kenneth David
分类号 A61K47/34;A01N25/34;B65D65/38;A61K9/00;A61K31/12;A61K31/192;A61K31/337;A61K31/4025;A61K31/4164;A61K31/4174;A61K31/427;A61K31/436;A61K31/497;A61K31/506;A61K31/65;A61K31/7036;A61M25/04;A61M31/00;A61M25/00 主分类号 A61K47/34
代理机构 McNair Law Firm, P.A. 代理人 McNair Law Firm, P.A. ;Lineberry Douglas L.
主权项 1. A bioactive, hydroforming, luminal liner composition comprising at least one crystalline, absorbable copolyester having a heat of fusion of at least 10 J/g and a molecular weight of greater than of 20 kDa; at least one liquid derivative of a polyether glycol; and at least one bioactive agent comprising an antifungal agent selected from the group consisting of ketoconazole, miconazole, voriconazole, and fluconazole.
地址 Anderson SC US
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