发明名称 |
Chemotherapy for drug-resistant cancer cells |
摘要 |
<p>The present invention relates to new treatments of multidrug resistant disorders, particularly cancers. There is provided a method of treating a cancer including administering an effective amount of a semicarbazone or hydrazone compound to a patient that has cancer, the cancer including a cancerous cell that includes an active efflux mechanism; wherein the compound is a substrate of the active efflux mechanism and the compound is able to form a chelation complex with a metal species in the cancerous cell, the chelation complex being cytotoxic to the cancerous cell.</p> |
申请公布号 |
AU2013350315(A1) |
申请公布日期 |
2015.06.04 |
申请号 |
AU20130350315 |
申请日期 |
2013.11.22 |
申请人 |
ONCOCHEL THERAPEUTICS LLC |
发明人 |
RICHARDSON, DES;JANSSON, PATRIC;YAMAGISHI, TETSUO |
分类号 |
A61K31/444;A61P35/00 |
主分类号 |
A61K31/444 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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