| 发明名称 |
STABLE COMPLEXES OF AN ALKALINE EARTH METAL SALT OF N5-METHYL-TETRAHYDROFOLIC ACID AND A POLYOL |
| 摘要 |
Complexes between an alkaline earth metal salt of (6RS)- or (6S)-N5-methyl-(5,6,7,8)-tetrahydrofolic acid and a polyol were prepared by lyophilization or spray-drying. These products were found to be stable compared with the active ingredient alone or the mixture of the same components prepared by means of other methodologies. |
| 申请公布号 |
US2015152110(A1) |
申请公布日期 |
2015.06.04 |
| 申请号 |
US201414516035 |
申请日期 |
2014.10.16 |
| 申请人 |
CERBIOS-PHARMA SA |
发明人 |
MEREU Andrea;Massara Maurizio;Vadala Alessandro |
| 分类号 |
C07D475/04 |
主分类号 |
C07D475/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stable complex between an alkaline earth metal salt of (6RS)- or (6S)-N5-methyl-(5,6,7,8)-tetrahydrofolic acid and a polyol. |
| 地址 |
Barbengo/Lugano CH |
