发明名称 |
PYRROLO SULFONAMIDE COMPOUNDS FOR MODULATION OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORGAMMA, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES |
摘要 |
<p>The invention provides modulators for the orphan nuclear receptor ROR³ and methods for treating ROR³ mediated diseases by administrating these novel ROR³ modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo sulfonamide compounds of Formula (1)
and the enantiomers, diastereomers, tautomers, solvates and pharmaceutically acceptable salts thereof.</p> |
申请公布号 |
EP2697197(B1) |
申请公布日期 |
2015.06.03 |
申请号 |
EP20120714232 |
申请日期 |
2012.04.13 |
申请人 |
PHENEX PHARMACEUTICALS AG |
发明人 |
STEENECK, CHRISTOPH;KINZEL, OLAF;GEGE, CHRISTIAN;KLEYMANN, GERALD;HOFFMANN, THOMAS |
分类号 |
C07D209/30;C07D207/36;C07D401/04;C07D403/04;C07D403/10 |
主分类号 |
C07D209/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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