发明名称 |
CROSSLINKED HYALURONIC ACID AND ITS PROCESS OF PREPARATION |
摘要 |
<p>The invention relates to a cross-linked hyaluronic acid that can be produced by a method comprising: (a) activating a hyaluronic acid; (b) reacting the activated hyaluronic acid with a cross-linking agent containing an oligo- or polypeptide in a reaction medium at a pH of between 8 and 12 in order to obtain a cross-linked hyaluronic acid; (c) adjusting the pH of the reaction medium to a value between 5 and 7; and (d) precipitating the cross-linked hyaluronic acid in an organic solvent. The invention also relates to the above method, to a hydrogel obtained from said cross-linked hyaluronic acid, and to the use of the cross-linked hyaluronic acid for the production of implants that can essentially be used in plastic surgery.</p> |
申请公布号 |
CA2668650(C) |
申请公布日期 |
2015.05.26 |
申请号 |
CA20072668650 |
申请日期 |
2007.10.25 |
申请人 |
STIEFEL LABORATORIES, INC. |
发明人 |
ASIUS, JEROME;RIVIERE, NICOLAS;ASIUS, BENEDICTE |
分类号 |
C08B37/08;A61L27/20 |
主分类号 |
C08B37/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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