发明名称 Methods for inhibiting prostate cancer by kinases and angiogenesis inhibitory mechanisms of ball moss extract
摘要 A method of treating prostate cancer by administering a pharmaceutically-acceptable amount of a crude extract of the indigenous Jamaican plant Ball Moss (Tillandsia Recurvata) comprising one or more cycloartane isolates, and the isolates used in the method for eliciting thereby a kinase inhibitory response of prostate cancer cells by selectively inhibiting MRCKα kinase and angiogenesis of (growth of new blood vessels) to reduce the viability of prostate cancer cells. The method and compounds holds promise as a chemopreventive agent, without causing excessive damage to normal cells.
申请公布号 US9040100(B2) 申请公布日期 2015.05.26
申请号 US201414270414 申请日期 2014.05.06
申请人 发明人 Lowe Henry;Bryant Joseph L.
分类号 A01N65/00;A61K31/575;A61K36/88 主分类号 A01N65/00
代理机构 Ober, Kaler, Grimes & Shriver 代理人 Ober, Kaler, Grimes & Shriver ;Craig Royal W.
主权项 1. An ethanol and dichloromethane extract of Jamaican ball moss.
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