发明名称 |
STABLE SOLID PREPARATION CONTAINING 4,5-EPOXYMORPHINAN DERIVATIVE |
摘要 |
<p>It is an object of the present invention to provide a stable solid preparation comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an effective ingredient. That is, the present invention provides the stable solid preparation comprising the 4,5-epoxymorphinan derivative or the pharmacologically acceptable acid addition salt thereof as the effective ingredient, and comprising sodium thiosulfate, a sugar or a sugar alcohol and hydroxypropylcellulose having a low degree of substitution in an amount of 1 to 30% by weight per weight of a unit containing the effective ingredient.</p> |
申请公布号 |
CA2685131(C) |
申请公布日期 |
2015.05.19 |
申请号 |
CA20082685131 |
申请日期 |
2008.04.25 |
申请人 |
TORAY INDUSTRIES, INC.;MARUHO CO., LTD. |
发明人 |
TAKAKI, SUGURU;OHTA, KOTOE;HORIUCHI, YASUHIDE;KOBAYASHI, MASATO;KAWASAKI, JUNKO;HORISAWA, EIJIRO |
分类号 |
A61K31/485;A61K9/14;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K47/02;A61K47/10;A61K47/26;A61K47/36;A61K47/38;A61P11/14;A61P17/04;A61P25/02 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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