发明名称 |
VACCINE NANOTECHNOLOGY |
摘要 |
PROBLEM TO BE SOLVED: To provide vaccine nanotechnology.SOLUTION: The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers.The present invention provides methods of designing, manufacturing, and using the inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof. |
申请公布号 |
JP2015091892(A) |
申请公布日期 |
2015.05.14 |
申请号 |
JP20150025608 |
申请日期 |
2015.02.12 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;PRESIDENT & FELLOWS OF HARVARD COLLEGE;BRIGHAM & WOMEN'S HOSPITAL INC;CHILDRENS MEDICAL CENTER CORP |
发明人 |
VON ANDRIAN ULRICH H;FAROKHZAD OMID C;LANGER ROBERT S;JUNT TOBIAS;MOSEMAN ELLIOTT ASHLEY;ZHANG LIANGFANG;BASTO PAMELA;IANNACONE MATTEO;ALEXIS FRANK |
分类号 |
A61K39/00;A61K9/127;A61K9/16;A61K38/00;A61K39/002;A61K39/02;A61K39/05;A61K39/08;A61K39/085;A61K39/09;A61K39/104;A61K39/106;A61K39/108;A61K39/112;A61K39/118;A61K39/12;A61K39/125;A61K39/145;A61K39/15;A61K39/155;A61K39/193;A61K39/20;A61K39/205;A61K39/21;A61K39/235;A61K39/245;A61K39/25;A61K39/275;A61K39/285;A61K39/29;A61K39/39;A61K39/395;A61K45/00;A61K47/14;A61K47/18;A61K47/24;A61K47/26;A61K47/28;A61K47/32;A61K47/34;A61K47/48;A61P1/04;A61P3/00;A61P3/10;A61P5/14;A61P11/06;A61P25/00;A61P25/30;A61P29/00;A61P31/00;A61P31/04;A61P31/06;A61P31/12;A61P31/14;A61P31/16;A61P31/18;A61P33/00;A61P33/02;A61P33/06;A61P35/00;A61P37/02;A61P37/08 |
主分类号 |
A61K39/00 |
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