发明名称 |
Anti-FOLR1 Immunoconjugate Dosing Regimens |
摘要 |
Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects. |
申请公布号 |
US2015132323(A1) |
申请公布日期 |
2015.05.14 |
申请号 |
US201414509809 |
申请日期 |
2014.10.08 |
申请人 |
IMMUNOGEN, INC. |
发明人 |
LUTZ ROBERT J.;PONTE JOSE |
分类号 |
C07K16/28;A61K47/48 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
|
主权项 |
1. A method for treating a human patient having an FOLR1-expressing cancer comprising administering to the patient an immunoconjugate which binds to FOLR1 polypeptide, wherein the immunoconjugate is administered at a dose of about 3.0 to about 7 milligrams (mg) per kilogram (kg) of body weight of the patient, wherein the kilograms of body weight of the patient are adjusted to adjusted ideal body weight (AIBW). |
地址 |
WALTHAM MA US |