发明名称 Anti-FOLR1 Immunoconjugate Dosing Regimens
摘要 Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.
申请公布号 US2015132323(A1) 申请公布日期 2015.05.14
申请号 US201414509809 申请日期 2014.10.08
申请人 IMMUNOGEN, INC. 发明人 LUTZ ROBERT J.;PONTE JOSE
分类号 C07K16/28;A61K47/48 主分类号 C07K16/28
代理机构 代理人
主权项 1. A method for treating a human patient having an FOLR1-expressing cancer comprising administering to the patient an immunoconjugate which binds to FOLR1 polypeptide, wherein the immunoconjugate is administered at a dose of about 3.0 to about 7 milligrams (mg) per kilogram (kg) of body weight of the patient, wherein the kilograms of body weight of the patient are adjusted to adjusted ideal body weight (AIBW).
地址 WALTHAM MA US
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