<p>A pharmaceutical combination comprising (a) a compound of formula (I), [Chemical formula should be inserted here as it appears on Abstract in paper form] or pharmaceutically acceptable salts thereof; and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway; the uses of such combination in the treatment or prevention of proliferative diseases; and methods of treating a subject suffering from a proliferative disease; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.</p>
申请公布号
AU2013341271(A1)
申请公布日期
2015.05.14
申请号
AU20130341271
申请日期
2013.11.06
申请人
CAO, ZHU;NOVARTIS AG
发明人
SHENG, QING;WANG, HUI-QIN;LI, FANG;LIANG, JINSHENG;CAO, ZHU ALEXANDER;MONAHAN, JOHN;VERSACE, RICHARD