| 发明名称 | Influenza hemagglutinin and neuraminidase variants | ||
| 摘要 | Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided. | ||
| 申请公布号 | US9028838(B2) | 申请公布日期 | 2015.05.12 |
| 申请号 | US201313784259 | 申请日期 | 2013.03.04 |
| 申请人 | MedImmune, LLC | 发明人 | Yang Chin-Fen;Kemble George |
| 分类号 | A61K39/145;C12N7/01;C07K14/005;C12N7/00;A61K39/00 | 主分类号 | A61K39/145 |
| 代理机构 | Grant IP, Inc. | 代理人 | Grant IP, Inc. |
| 主权项 | 1. A 6:2 reassortant influenza virus, wherein said virus comprises 6 internal genome segments from A/Ann Arbor/6/60 and 2 surface antigen genome segments, wherein the surface antigen genome segments encode an HA and a NA polypeptide, wherein the surface antigen genome segment that encodes the HA polypeptide produces a polypeptide comprising the amino acid sequence of SEQ ID NO:29. | ||
| 地址 | Gaithersburg MD US | ||