发明名称 |
PREPARATION METHOD OF PYRANO COUMARIN DERIVATIVES CATALYZED BY BISMUTH SALTS |
摘要 |
The present invention relates to a method for producing pyranocoumarin derivative using a bismuth catalyst. More specifically, the pyrano[3,2-c]coumarin derivative is produced by making a propargyl alcohol compound react with a 4-hydroxy coumarin compound in the presence of the bismuth triflate catalyst. According to the present invention, the method can redress drawback of the prior method that the yield is low because strong acid, generating the large amount of by product, is used. Moreover, the method includes simplified reaction steps. Therefore, the pyrano[3,2-c]coumarin derivative can be produced at a high yield by the method. |
申请公布号 |
KR101519011(B1) |
申请公布日期 |
2015.05.11 |
申请号 |
KR20140001717 |
申请日期 |
2014.01.07 |
申请人 |
KNU-INDUSTRY COOPERATION FOUNDATION |
发明人 |
LEE, KOO YEON;LEE, PHIL HO;KIM, JAE HYUN;PARK, JUNG MIN;YUN, JI HEE |
分类号 |
C07D493/04;A61K31/37;A61P29/00;A61P31/00 |
主分类号 |
C07D493/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|