发明名称 PROTEIN AQUEOUS SUSPENSION
摘要 The objective of the present invention is to provide, for a wide range of proteins, an aqueous suspension which comprises a protein complex that can be concentrated and has high stability. The present invention is an aqueous suspension in which a protein and a polyamino acid that have surface charge in a buffer solution form a complex and are suspended, wherein the protein can be concentrated by removing at least a portion of water from the complex-containing aqueous suspension and wherein in the complex, the protein has at least one of shaking stress resistance, flow enhancement, oxidation resistance, thermal stability and aggregation inhibition properties.
申请公布号 WO2015064591(A1) 申请公布日期 2015.05.07
申请号 WO2014JP78667 申请日期 2014.10.28
申请人 TERUMO KABUSHIKI KAISHA 发明人 IZAKI SHUNSUKE;KIMOTO TOMOAKI;HANDA KENJI;MIEDA SHIUHEI;SHIRAKI KENTARO;KURINOMARU TAKAAKI;MARUYAMA TAKUYA
分类号 A61K38/00;A61K9/08;A61K9/10;A61K38/22;A61K38/43;A61K39/395;A61K47/12;A61K47/34;C07K1/00;C07K14/52;C07K14/575;C07K16/00;C07K19/00;C12N9/00 主分类号 A61K38/00
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