发明名称 |
Compositions and methods for treating glioblastoma GBM |
摘要 |
<p>Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3; and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.</p> |
申请公布号 |
AU2011204407(B2) |
申请公布日期 |
2015.05.07 |
申请号 |
AU20110204407 |
申请日期 |
2011.01.05 |
申请人 |
VASCULAR BIOGENICS LTD. |
发明人 |
COHEN, YAEL;BANGIO, LIVNAT;BRENNER, ANDREW J.;BREITBART, EYAL |
分类号 |
C12N15/00;C07H21/02 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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