发明名称 |
METHODS OF DETERMINING BREAST CANCER PROGNOSIS |
摘要 |
Disclosed herein are methods of determining a diagnosis or prognosis for a subject with a breast tumor. In one embodiment, the method includes determining an amount of EPS8-like 1 (EPS8L1) in the sample (such as an amount of EPS8L1 nucleic acid or protein) and comparing the amount of EPS8L1 in the sample to a control. The subject is determined to have a poor prognosis (such as decreased likelihood of survival) if the amount of EPS8L1 in the sample is increased compared to the control. In some embodiments, the methods further include administering a treatment to a subject determined to have a poor prognosis, such as administering an ErbB2-targeting therapy to the subject. |
申请公布号 |
WO2015061577(A1) |
申请公布日期 |
2015.04.30 |
申请号 |
WO2014US61981 |
申请日期 |
2014.10.23 |
申请人 |
OREGON HEALTH & SCIENCE UNIVERSITY |
发明人 |
RANTALA, JUHA;GRAY, JOE, W. |
分类号 |
G01N33/53;C12Q1/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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