| 发明名称 |
Compuestos derivados de pirimidin-amina o triazin-amina, inhibidores de adn-pk; composicion farmaceutica; y su uso para el tratamiento del cancer. |
| 摘要 |
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. |
| 申请公布号 |
CL2014002873(A1) |
申请公布日期 |
2015.04.24 |
| 申请号 |
CL20140002873 |
申请日期 |
2014.10.24 |
| 申请人 |
VERTEX PHARMACEUTICALS, INC. |
发明人 |
GAO, HUAI;CHARIFSON PAUL S.;COTTRELL KEVIN MICHAEL;DUFFY JOHN P.;GIROUX SIMON;GREEN JEREMY;JACKSON KATRINA LEE;MAXWELL JOHN PATRICK;MORRIS MARK A.;PIERCE ALBERT CHARLES;WAAL NATHAM D.;LAUFFER DAVID J.;KENNEDY JOSEPH M.;LEDEBOER MARK WILLEM;XU LI PAN;XU JINWANG;DENG HONGBO |
| 分类号 |
C07D239/42;A61K31/505;A61K31/53;A61P35/00;C07D401/04;C07D401/14;C07D403/04;C07D403/10 |
主分类号 |
C07D239/42 |
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