| 发明名称 |
IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF |
| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide a novel method for determining the level of inflammatory bowel disease.SOLUTION: There is provided a method of determining the seriousness level of inflammatory bowel disease by detecting reduction in the amount of polypeptides including a specific amino acid sequence in a sample of, e.g., colon derived cells obtained from a mammal. This method can be used also for the amount of polypeptides including another specific amino acid sequence in the sample, and the amount of IL-17.</p> |
| 申请公布号 |
JP2015077137(A) |
申请公布日期 |
2015.04.23 |
| 申请号 |
JP20140243369 |
申请日期 |
2014.12.01 |
| 申请人 |
GENENTECH INC |
发明人 |
CHEN JIAN;ELLEN FILVAROFF;SHERMAN FONG;GODDARD AUDREY;PAUL J GODOWSKI;GRIMALDI J CHRISTOPHER;GURNEY AUSTIN L;LI HANZHONG;HILLAN KENNETH J;TUMAS DANIEL;MENNO VAN LOOKEREN;RICHARD L VANDLEN;WATANABE COLIN K;WILLIAMS P MICKEY;WOOD WILLIAM I;YANSURA DANIEL G |
| 分类号 |
C12Q1/68;A61K31/70;A61K38/17;A61K38/20;A61K39/395;C07K14/54;C07K14/715;C07K16/24;C07K16/28;C12N15/12;C12N15/62;G01N33/53;G01N33/566;G01N33/68 |
主分类号 |
C12Q1/68 |
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