发明名称 T CELL EPITOPES FROM COCKROACH AND METHODS OF MAKING AND USING SAME
摘要 The invention provides Cockroach proteins, peptides, subsequences, portions, homologues, variants and derivatives thereof, and methods and uses and medicaments of such proteins, peptides, subsequences, portions, homologues, variants and derivatives thereof. Such methods, uses and medicaments include modulating an immune response, protecting a subject against or treating a subject for an allergic response, allergic disorder or allergic disease and inducing immunological tolerance to the allergen (e.g., Cockroach allergen) in a subject.
申请公布号 US2015110819(A1) 申请公布日期 2015.04.23
申请号 US201314398719 申请日期 2013.05.03
申请人 LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY 发明人 Sette Alessandro;Peters Bjoern;Greenbaum Jason
分类号 C07K14/435;G01N33/569;A61K39/35 主分类号 C07K14/435
代理机构 代理人
主权项 1. A protein or peptide having a length of from 7 to 30 amino acids and an amino acid sequence comprising, consisting of or consisting essentially of an amino acid sequence set forth in Table I (SEQ ID NOs. 1-25) or Table VII (SEQ ID NOs. 26-57), or a subsequence, portion, homologue, variant or derivative thereof.
地址 La Jolla CA US