发明名称 Antibiotic peptide analogues with high activities against multidrug resistant bacteria and fungi and anti-inflammatory activities designed from Protaetiamycine, and their uses
摘要 The present invention relates to 7 types of antibiotic peptides whose sequence number is 1 to 7, which are manufactured by basing an antibiotic peptide made from 9 residual sequences in a α-helix region of Protaetiamycine separated from the larva of Protaetiabrevitarsis and accordingly have an antimicrobial activity and an anti-inflammatory activity while reducing cell toxicity, and mechanism thereof wherein two novel antimicrobial peptides have an outstanding effect of removing drug resistance bacteria and bacteria causing pimples and an anti-inflammatory activity without cell toxicity, thereby being used as an antimicrobial drug and an antifungal drug.
申请公布号 KR20150042447(A) 申请公布日期 2015.04.21
申请号 KR20130121083 申请日期 2013.10.11
申请人 건국대학교 산학협력단 发明人 김양미;이은정
分类号 A61K38/08;A61P31/00;C07K7/06 主分类号 A61K38/08
代理机构 代理人
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