| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for efficiently producing L-carnitine having a very high purity.SOLUTION: The method includes: (a) preparing a solution comprising at least 5% (w/w) carnitine in a first solvent and in which the carnitine is a mixture of D-carnitine and L-carnitine; (b) administering a L-carnitine crystal into the solution; (c) adding a second solvent in which L-carnitine is insoluble or does not have a low solubility; and (d) isolating crystals comprising L-carnitine. The first solvent is selected from ethanol, methanol, water, acetonitrile or a mixture thereof, and the second solvent is selected from acetone, isopropanol, iso-butanol, 2-propanol, 1-pentanol, 2-butanone, methyl acetate, ethyl acetate, butyl acetate, tetrahydrofuran, toluene or a mixture thereof. |
