发明名称 |
High viscosity macromolecluar compositions for treating ocular conditions |
摘要 |
Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions include MAAC solutions or particles present in a therapeutically effective amount, a viscosity-inducing component, and an aqueous carrier component. The compositions have viscosities at about 25°C. of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity at 25°C. is in the range of from about 80,000 cps to about 300,000 cps. |
申请公布号 |
EP2606899(B1) |
申请公布日期 |
2015.04.15 |
申请号 |
EP20120199057 |
申请日期 |
2008.04.28 |
申请人 |
ALLERGAN, INC. |
发明人 |
HUGHES, PATRICK M.;DE VRIES, GERALD W.;LYONS, ROBERT T.;TROGDEN, JOHN T.;WHITCUP, SCOTT M. |
分类号 |
A61K31/713;A61K9/00;A61K9/08;A61K38/39;A61K39/00;A61K39/395;A61K47/34;A61K47/36;A61P27/02;C07K16/22;C12N15/113 |
主分类号 |
A61K31/713 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|