1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES

摘要

There are represented 1H-imidazo[4,5-c] quinolinone derivatives of formula (1), values of X substitute thereof is O or S; Y is CH or N; R1 is substituted or unsubstituted with 5-member heteroaryl; R2 is hydrogen, C1-C4 is alkyl or C2-C4 alkynile, R3 is substituted or unsubstituted with aryl or heterocyclile; or pharmaceutically acceptable salt thereof, solvate or hydrate; pharmaceutical compositions on basis thereof, and application thereat the treatment of diseases dependent on protein- and/or lipidkinase. Table: 92