| 发明名称 |
HETEROCYCLYL PYRIMIDINE ANALOGUES AS TYK2 INHIBITORS |
| 摘要 |
The present invention relates to compounds of formula (I) wherein R, R1, X1 to X5 have the meaning as cited in the description and the claims. Said compounds are useful as TYK2 inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds as well as their use as medicaments. |
| 申请公布号 |
EP2855451(A1) |
申请公布日期 |
2015.04.08 |
| 申请号 |
EP20130724816 |
申请日期 |
2013.05.23 |
| 申请人 |
CELLZOME LIMITED |
发明人 |
HARRISON, RICHARD JOHN;RAMSDEN, NIGEL;MAJOR, JEREMY;MOREL, ADELINE;CONVERY, LAURA;SUNOSE, MIHIRO;LYNCH, ROSEMARY;ADREGO, RITA;JONES, ALISON |
| 分类号 |
C07D401/14;A61K31/505;A61P37/00;C07D403/12;C07D405/14;C07D413/14 |
主分类号 |
C07D401/14 |
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