Identificación de linfocitos T reguladores mediante el regulador del gen global SatB1
摘要
<p>The present invention provides a method for the identification of regulatory T cells based on the diminished abundance or even absence of the global gene regulator SATB1 in such regulatory T cells. In particular, the invention relates to a method utilizing ligands that specifically bind to SATB1 for identifying regulatory T cells which are cells showing a reduced binding to said ligand. Such method is suitable for quality determination of a regulatory T cell population. The invention further provides a kit or diagnostic composition for such method.</p>
申请公布号
ES2533185(T3)
申请公布日期
2015.04.08
申请号
ES20120166847T
申请日期
2010.04.06
申请人
BECTON DICKINSON AND COMPANY;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITÄT BONN
发明人
SCHULTZE, JOACHIM LUDWIG;BEYER, MARC DANIEL;WARNER, NOEL;BALDERAS, ROBERT