发明名称 |
IMIDAZO[1,2-A]PYRIDIN-7-AMINES AS IMAGING TOOLS |
摘要 |
The present invention relates to compounds of general formula (I) wherein R1 is lower alkyl or lower alkyl substituted by halogen; R2, R3 are hydrogen or tritium; or to a pharmaceutically acceptable acid addition salt. The compounds may be used for binding and imaging tau aggregates and related beta-sheet aggregates including besides others beta-amyloid aggregates or alpha-synuclein aggregates. |
申请公布号 |
CA2920068(A1) |
申请公布日期 |
2015.04.02 |
申请号 |
CA20142920068 |
申请日期 |
2014.09.23 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
GOBBI, LUCA;KNUST, HENNER;KOERNER, MATTHIAS;MURI, DIETER |
分类号 |
C07D471/04;A61K31/4353;A61K31/437;A61P25/28 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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