发明名称 IMIDAZO[1,2-A]PYRIDIN-7-AMINES AS IMAGING TOOLS
摘要 The present invention relates to compounds of general formula (I) wherein R1 is lower alkyl or lower alkyl substituted by halogen; R2, R3 are hydrogen or tritium; or to a pharmaceutically acceptable acid addition salt. The compounds may be used for binding and imaging tau aggregates and related beta-sheet aggregates including besides others beta-amyloid aggregates or alpha-synuclein aggregates.
申请公布号 CA2920068(A1) 申请公布日期 2015.04.02
申请号 CA20142920068 申请日期 2014.09.23
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GOBBI, LUCA;KNUST, HENNER;KOERNER, MATTHIAS;MURI, DIETER
分类号 C07D471/04;A61K31/4353;A61K31/437;A61P25/28 主分类号 C07D471/04
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