发明名称 |
ACID ADDITION SALT OF IRINOTECAN |
摘要 |
<p>The present invention is directed to an irinotecan acid addition salt which is formed through addition of an acid selected from the group consisting of sulfuric acid, nitric acid, phosphoric acid, methanesulfonic acid, citric acid, maleic acid, and succinic acid to irinotecan, to a method for producing the salt, and to a pharmaceutical composition containing the salt. The addition salt requires no heating process during drug preparation and provides an aqueous drug product in which the salt is stably dissolved.</p> |
申请公布号 |
EP1798235(B1) |
申请公布日期 |
2015.04.01 |
申请号 |
EP20050788121 |
申请日期 |
2005.09.29 |
申请人 |
KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
SHIMIZU, HIDEAKI;UCHIDA, MIYUKI;SAWADA, SEIGO;KANEDA, NORIMASA;MATSUMOTO, TSUNEO |
分类号 |
C07D491/22;A61K31/4745;A61P35/00 |
主分类号 |
C07D491/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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