The present invention provides compounds of Formula (X):(Formula (X), or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
申请公布号
SG11201500271U(A)
申请公布日期
2015.03.30
申请号
SG11201500271U
申请日期
2013.08.02
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
YANG, WU;CORTE, JAMES, R.;GILLIGAN, PAUL, J.;PINTO, DONALD, J.P., PINTO;EWING, WILLIAM, R.;DILGER, ANDREW, K.;WANG, YUFENG;FANG, TIANAN;PABBISETTY, KUMAR, B.;SMITH II, LEON, M.