发明名称 FORMULATION FOR ANTI-α4β7 ANTIBODY
摘要 <p>Antibody formulations are described comprising a mixture of an anti-α4β7antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.</p>
申请公布号 TN2013000455(A1) 申请公布日期 2015.03.30
申请号 TN20130000455 申请日期 2013.10.31
申请人 MILLENNIUM PHARMACEUTICALS INC 发明人 DILUZIO WILLOW;PALANIAPPAN VAITHIANATHAN;BROWN JASON;FOX IRVING H;SCHOLZ CATHERINE;NGUYEN PHUONG M;VARGA CSANAD M;JENKINS HELEN;ROSARIO MARIA
分类号 A61K39/395 主分类号 A61K39/395
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