发明名称 |
Pharmaceutical composition of (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxy propyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration therof |
摘要 |
<p>Provided is a pharmaceutical composition comprising (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide (formula 1), a filler, a diluent, a disintegrant, and a glidant in the form of a tablet. The pharmaceutical composition may be used in the treatment of cystic fibrosis.</p> |
申请公布号 |
NZ606805(A) |
申请公布日期 |
2015.03.27 |
申请号 |
NZ20110606805 |
申请日期 |
2011.08.22 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
ALARGOVA ROSSITZA GUEORGUIEVA;DUNBAR CRAIG ANTONY;KADIYALA IRINA NIKOLAEVNA |
分类号 |
A61K9/20;A61K31/404 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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