Fast Diagnosis and Personalized Treatment for Acne

摘要

Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne include administering an effective amount of a drug specifically targeting RT4, RT5, RT7, RT8, RT9, or RT10, such as small molecules, antisense molecules, siRNAs, biologics, antibodies, phages, vaccines, or combination thereof.

主权项

1. The method of claim 3, wherein:
amplifying bacterial DNA comprises amplifying 16S ribosomal DNA in said sample; typing the subject's DNA comprises sequencing said amplified DNA products and determining whether the DNA sequences correspond to one or more of the ten major ribotypes (RTs) of P. acnes strains, RT1-RT10 (SEQ ID NOs 1-10).