| 主权项 |
1. A compound of formula (Ia), or a pharmaceutically acceptable salt thereof: wherein R1 is selected from the group consisting of H, C1-3alkyl, C1-3alkoxy, CF3, and halo; R2, R3 and R4 are H; R5 is C1-3alkyl; R6 is C3-5alkyl or —CH2C3-4cycloalkyl; R7 is selected from the group consisting of: each R8 is independently selected from the group consisting of halo, C1-6alkyl, C1-6alkoxy, C3-6cycloalkyl, CN, OH, C(O)OH, C(O)OC1-3alkyl and CH2OH; R9 is the group —(CHR10)s—(X)t—(CHR10)u—R11; each R10 is independently selected from H, CH3, OH and CH2OH; X is CH2, NH or O; R11 is a heterocycloalkyl or C3-6cycloalkyl group which may be unsubstituted or substituted with one or more substituents independently selected from the group consisting of CH3, OMe, OH, CH2OH and halo; r is 0, 1 or 2; s is 0, 1 or 2; t is 0 or 1; u is 0, 1 or 2; with the proviso that no more than two R10 groups represent CH3, OH or CH2OH. |
