| 摘要 |
PROBLEM TO BE SOLVED: To provide a new compound having selective breton type tyrosine kinase inhibitory activity, having excellent metabolic stability, also having low hepatotoxicity and capable of being made into a safe therapeutic agent for the disease of B cells and mast cell participation.SOLUTION: Provided is 6-amino-9-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purine-8-on expressed by the following formula or its salt. |
