发明名称 |
NOVEL COMPOSITIONS |
摘要 |
The present invention relates to particular immunogenic compositions comprising a gp120 related polypeptide and an adjuvant, wherein the adjuvant comprises a saponin and a lipopolysaccharide. Such compositions are substantially free of a NefTat related polypeptide, comprise between 10-40ug of a lipopolysaccharide and between 10-40ug of an immunologically active saponin fraction derived from the bark of Quillaja Saponaria Molina presented in the form of a liposome or have a concentration of sodium chloride of 130 mM or lower. |
申请公布号 |
CA2851871(A1) |
申请公布日期 |
2015.03.16 |
申请号 |
CA20142851871 |
申请日期 |
2014.05.08 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
BOURGUIGNON, PATRICIA B.;KOUTSOUKOS, MARGUERITE CHRISTINE;LORIN, CLARISSE MARIE-MADELEINE |
分类号 |
C12N15/49;A61K36/185;A61K39/21;A61K39/39;A61P31/18;A61P37/04;C07K14/16;C12N7/01;C12N15/86 |
主分类号 |
C12N15/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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