发明名称 MALE PATTERN BALDNESS EVALUATION MODEL
摘要 <p>Provided is a method for accelerating transition from the anagen to the catagen phase of the hair cycle in rodents, the method comprising a step for administering testosterone to rodents. Also provided is a method for evaluating drug efficacy in rodents, the method comprising (a) a step for inducing a synchronized anagen phase in the telogen phase of the hair cycle, (b) a step for administering testosterone, (c) a step for administering a drug, and (d) a step for evaluating the extent to which drug administration inhibits transition from the anagen phase to the catagen phase in the hair cycle of rodents which has been accelerated by testosterone administration. The efficacy of a trichogen or hair tonic can be efficiently evaluated by the simple in vivo male pattern baldness model of the present invention.</p>
申请公布号 WO2015033874(A1) 申请公布日期 2015.03.12
申请号 WO2014JP72790 申请日期 2014.08.29
申请人 TAISHO PHARMACEUTICAL CO., LTD. 发明人 NAKAO AKIKO;UEDA YASUJI;MAKIHARA SHIRO
分类号 C12Q1/00;A61K8/63;A61K31/568;A61K31/5685;A61K38/22;A61P17/14;A61Q7/00;G01N33/15 主分类号 C12Q1/00
代理机构 代理人
主权项
地址
您可能感兴趣的专利