| 摘要 |
<p>The present application provides a method and aqueous composition for stabilizing and isolating nucleic acid from whole blood or blood fraction samples. The method and aqueous composition can be used to stabilize and isolate nucleic acid from whole blood, plasma, buffy coat or total white blood cell isolates. The aqueous composition can comprise a denaturing agent, a chelating agent and a buffering agent, preferably in the absence of a chaotrope, and at a pH greater than 5.0. The samples can be stored at varying temperatures, preferably at room temperature, and for prolonged lengths of time while maintaining integrity of the nucleic acid.</p> |
