| 发明名称 | Method for cancer detection | ||
| 摘要 | The present invention relates to the diagnosis and treatment of cancer, and specifically to a method of diagnosing the presence, status or metastasis of cancer by detecting plasma Hsp90α having the amino acid sequence of SEQ ID NO:1 as a tumor marker. In addition, the present invention also relates to a method for the treatment of cancer and metastasis. | ||
| 申请公布号 | US8975030(B2) | 申请公布日期 | 2015.03.10 |
| 申请号 | US201313784186 | 申请日期 | 2013.03.04 |
| 申请人 | Tsinghua University;Protgen Ltd. | 发明人 | Luo Yongzhang;Song Xiaomin;Wang Xiaofeng;Zhuo Wei;Chang Guodong;Fu Yan |
| 分类号 | G01N1/00;G01N33/00;G01N33/48;G01N33/53;G01N33/566;G01N33/68;C07K14/47;C07K16/18;G01N33/574;A61K39/395 | 主分类号 | G01N1/00 |
| 代理机构 | Rothwell, Figg, Ernst & Manbeck, P.C. | 代理人 | Rothwell, Figg, Ernst & Manbeck, P.C. |
| 主权项 | 1. A method of determining the presence of cancer, the metastasis of cancer, the prognosis of cancer, or the efficacy of a cancer treatment in at least one subject in need thereof which comprises specifically detecting the level of the polypeptide of SEQ ID NO:1 in a plasma sample of said subject wherein a plasma level of SEQ ID NO:1 of 2-10 ng/mL indicates non-cancer, a plasma level of SEQ ID NO:1 of greater than 50 ng/mL indicates the presence of cancer, a plasma level of SEQ ID NO:1 of greater than 200 ng/mL indicates the presence of cancer metastasis, and a maintained or increased plasma level of SEQ ID NO:1 in a cancer patient indicates poor prognosis. | ||
| 地址 | Beijing CN | ||